The Marburg amalgam detoxification study


Bernhard A. Weber, Regina Schneider


Since 1992 the private Marburg Institute for Naturopathic Medicine offers amalgam information in several cities and since 1994 it offers a nationwide telephonic amalgam advice service(06421/66379).


Investigations on more than 1200 patients have shown a chronic mercury poisoning from amalgam fillings. About 50 % of those patients removed their amalgam fillings after the investigation.

130 patients finished the detoxificational therapy by now. They were questioned for improvement of their symptoms and were investigated again.

According to the intensity of the detoxification, 80 % of the patients showed a good or even excellent improvement of symptoms.

These results show distinctly the dangerousness of amalgam fillings.

In Germany more than 50 million people have amalgam fillings. In the age group between 20 and 50 years most of them have more than 10 fillings. Here, our preventive health care system has failed completely (one reason for this are the publicity campaigns of the sugar industry).

Our own study „allergies and amalgam poisoning“ has already in 1994 shown a high probability of a connection between amalgam fillings and allergies.

Therapeutic studies of Perger, Friese and american investigators (R.L.Silberud)(number of cases = 1200) shall now be proved by our own study. In more than 95% of our cases mild and naturopathic drugs were used to detoxificate the patients from the accumulated heavy metals. Naturopathic diagnosis and mild detoxification in consideration of the associated and secondary diseases have been the aim of our study.

Surprisingly high was the large number of severe chronic patients, even in the age group of the 20 to 40 years old. Not only the enormous and most expensive increase of the often amalgam caused allergies, but also chronic diseases of the immunologic and nervous system are one major reason for the increase of costs in our public health service.  This shows that the decision pro or contra amalgam has also a profound meaning for all the healthy people who have to pay their contribution to the health insurances.

This is another important reason why we have collected the data of the „Marburg detoxification study“, which is a substantial evidence in the discussion of a probition of the use of amalgam.



About the Institute

The private Institute for Naturopathic Medicine in Marburg is organized as a non profit organisation. The staff of the institute consists of four doctors, four other employees offering health information, another four employees occupied with various functions and many more helpers and sponsors. It is financed by the contributions of the members, the treatment fees that are paid by the patients and money from a job creation scheme, offered by the german government. The main aim of our work, is besides the public relations, the realization of studies to naturopathic and environmental medicine.

Impetuous discussions about the possible damage through chronic mercury poisoning from amalgam filings are more and more leading to increased restrictions in the use of this material by the german „Amt für Arzneimittelsicherheit“ (official board for the security of drugs).

Drasch, from the University of Munich, was able to show that one can find increased mercury values in the tissues of brain, liver and kidney of a patient with a high number of amalgam fillings.

In countless publications Daunderer has introduced a mobilisation test (based on DMPS) for diagnostic purposes. In his „Handbuch der Amalgamvergiftung“ (handbook for amalgam poisoning) he presents therapeutic successes of detoxification in individual cases.

About the history of amalgam in medicine


Historically, mercury poisonings with therapeutic aims were known already a long time before modern medicine. An important motive for Hahnemann to develop homeopathy nearly 200 years ago now, was the excessive use of mercury ointments by quacks, which caused enormous chronic poisonings. (Interestingly, the german word for quack „Quacksalber“ has been derived and changed only in two vocals from the word „Quecksilber“, which means mercury.)

Amalgam, which has been introduced into medical practice around 1830 and already at that time has led to a temporary prohibition, still consists of more than 50% mercury (plus about 30% silver, 20% tin and rarely copper).

In 1925 Prof. Stock, Berlin, has presented distinct evidence for chronic poisonings from amalgam.

Naturopathic therapists have warned for decades, because of their own experience, of this „cheap“ solution.

Are diseases caused by poisoning with amalgam traceable ?

å Besides the proof of poison in body tissues (Drasch, Daunderer) and the mobilisation of mercury by means of certain substances (Daunderer, Pergerer), only large studies will help us here.

å The Marburg amalgam detoxification study provides us with a good basis and many arguments in the discussion against the use of amalgam.

å One hindrance to the proof of the bad effects of amalgam is the enormous variety of symptoms of a chronic mercury poisoning and the other often interfering ingredients tin, copper and silver.

Hahnemann listed already in 1830 about 1260 different symptoms. Thomsen und Kramer have documented this variety from the view of a dentist.

å Table 1 shows a synopsis of our questionnaire (symptoms):

Table 1

mouth symptoms

gingiva bleeding                                                severe ¨   still passable ¨  moderate ¨   no grinding of teeth                                                                                         severe ¨   still passable ¨  moderate ¨   no ¨

glossopyrosis                                                    severe ¨   still passable ¨  moderate ¨   no ¨

dry mouth                                                       severe ¨   still passable ¨  moderate ¨   no ¨

metallic taste                                                     severe ¨   still passable ¨  moderate ¨   no


contact eczema                                               severe ¨   still passable ¨  moderate ¨   no ¨

food allergy                                                     severe ¨   still passable ¨  moderate ¨   no ¨

hay fever                                                         severe ¨   still passable ¨  moderate ¨   no ¨

eczema (neurodermatitis)                                 severe ¨   still passable ¨  moderate ¨   no ¨

asthma/chronic bronchitis                                 severe ¨   still passable ¨  moderate ¨   no ¨

itching/pruritus                                                 severe ¨   still passable ¨  moderate ¨   no ¨

chronic/frequent infections or inflammatory irritations

nose                                                                severe ¨   still passable ¨  moderate ¨   no ¨

paranasal sinuses                                             severe ¨   still passable ¨  moderate ¨   no ¨

pharynx                                                           severe ¨   still passable ¨  moderate ¨   no ¨

chronic headache/migraine                                severe ¨   still passable ¨  moderate ¨   no ¨

77vertigo                                                          severe ¨   still passable ¨  moderate ¨   no ¨

low blood pressure                                          severe ¨   still passable ¨  moderate ¨   no ¨

neurologic symptoms                                        

aboulia/fatigue                                                   severe ¨   still passable ¨  moderate ¨   no ¨

lack of concentration                                        severe ¨   still passable ¨  moderate ¨   no ¨

depressive mood                                             severe ¨   still passable ¨  moderate ¨   no ¨

extreme nervousness                                        severe ¨   still passable ¨  moderate ¨   no ¨

insomnia                                                          severe ¨   still passable ¨  moderate ¨   no ¨

tremor                                                             severe ¨   still passable ¨  moderate ¨   no ¨

dysopia                                                           severe ¨   still passable ¨  moderate ¨   no ¨

tinnitus                                                           severe ¨   still passable ¨  moderate ¨   no ¨

arrhythmias                                                     severe ¨   still passable ¨  moderate ¨   no ¨

increased sweating                                          severe ¨   still passable ¨  moderate ¨   no ¨

aching back                                                     severe ¨   still passable ¨  moderate ¨   no ¨

rheuma                                                             severe ¨   still passable ¨  moderate ¨   no ¨

acne (n = 70)                                                   severe ¨   still passable ¨  moderate ¨   no ¨

alopecia/loss of hair                                          severe ¨   still passable ¨  moderate ¨   no ¨

urgency                                                           severe ¨   still passable ¨  moderate ¨   no ¨

constipation                                                     severe ¨   still passable ¨  moderate ¨   no ¨

meteorism                                                       severe ¨   still passable ¨  moderate ¨   no ¨

diarrhea                                                          severe ¨   still passable ¨  moderate ¨   no ¨

inflammation of the eye                                   severe ¨   still passable ¨  moderate ¨   no ¨

other diseases or complaints                            ____________________________________


In our pilot study we are trying, by means of a large number of patients, to achieve a statement even in the case of the rare symptoms, whether an amalgam removal and a detoxification therapy improves these symptoms.

All of the 1200 patients investigated until September 1995 in our amalgam information centres in Marburg, Gießen, Fulda and Koblenz filled out the above shown questionnaire at the beginning. Afterwards we have tested the patients with the electroacupuncture according to Voll (EAV) testing method. We investigated the amalgam stress at the acupuncture points of the mainly involved organs and organic systems: lymph sytem, allergy and nervous system. In addition we examined the individually severely stressed meridians.


diagnostic methods

The high accuracy of the diagnostic method electroacupuncture according to Voll has been shown in several studies, including our own blindstudy in 1993.

In a small part of the cases investigated with this method, a mobilisation with DMPS and a chemical diagnosis of the urine followed the initial examination in order to prove the diagnosis and at the same time start an intensive therapy.

70% of our study patients have made a patch test, to see if they are allergic to amalgam. Only 8 - 15% do have a positive test result in such patch tests, as it can be read in international literature.

Dependent on the seriousness of the symptoms of the individual patients we either chose to treat intensively (if the patients agreed) with the chelating agent DMPS (DMSA) or we led through a naturopathic detoxification with homeopathy/phytotherapy, the vitamines ACE, the trace elements zinc and selenium, as well as with amino acids and gluthatione.

From the more than 1200 patients 200 were reexamined directly and 420 patients, who had been examinated before October 1994 were asked to fill out our questionnaire. 266 filled out questionnaires have returned to us by now.

For the evaluation we separated those patients who did not get a detoxificational or any other therapy from the others.

The evaluation of the first 130 patients, who removed their amalgam and who completed a detoxification, gives us the chance to make a relatively clear statement.

Concerning some single symptoms we have to admit that the frequency sometimes was to small to allow a proper interpretation. Here, we have to supplement our pilot study to make it able to provide us with more reliable data.

From all of the 130 patients in the study, 30% were investigated thoroughly with electroacupunture according to Voll (EAV) in order to detect and treat most of the associated diseases.

In 70% of our patients we did only an EAV short test, in which we regularly searched for the amalgam related secondary disease intestinal dysbacteria and chemical stress (formaldehyde, PCP, PCB, lindane) as well.

Naturally we prefer the comprehensive and more valid long EAV test in order to obtain a more holistic view of a patient and to be able to offer a better therapy.

The evaluation of the occured improvements of symptoms was measured in following degrees: extremely better - better - slightly better - no (if a symptom was not measurable at all).

diagnostic methods (summary)

å questionnaire (table 1)

å subsequent questionnaire (similar to table 1)

å DMPS test (only for one group of patients): urinanalysis -> mobilisation with one ampule

     DMPS (Heyl) -> urinanalysis 2 after 40 minutes

å patch test (Hermal) -> sometimes by dermatologists .

electroacupunture according to Voll (EAV)

å The acupuncture points und the meridian-organ systems were the starting-point for Dr.Voll to develop a very comprehensive and holistic system diagnostics. Heine cleared up in 1987 the histologic structure of the acupuncture points. By discovering numerous new points a precise diagnostics of all parts and functions of the human body was made possible. Although already some studies to this method, which is used world-wide, were published (Weber), it is not yet acknowledged scientifically.

å The resonance- or medicament-test of EAV is the second important component of this combination of acupuncture and homeopathy. Countless chronic stress factors (environmental or from past diseases) can be measured with this method. An accurate and most of the time homeopathic or orthomolecular therapy is rendered possible through this. A clearly arranged survey and introduction to EAV is offered by H.Rossmann or a script of our institute.

å The high accuracy of EAV in the case of amalgam is well demonstrated by our own blindstudy (1993; Danz, Leber, Schneider, Weber).

Even a rather precise semi-quantitive measurement of therapy success over several months is made possible by EAV.

The inclusion of the low-potency test substances D3 and D5 yields distinct differences in the test value improvement. At the points for the lymphatic system, intestine, nervous system, and allergy we often can measure a pathologic value of more than 80 with a clear pointer drop, which can be compensated with a test ampule of silver amalgam D4 up to the ideal value of 50. After one month of therapy we often find only a value improvement with a D4 ampule up to 60. It now often needs a D6 ampule to compensate on 50. After 3 months of therapy the chosen parameter is around 70 without a pathologic pointer drop. The test substance now needs very high potencies to compensate the value again on 50.

In some patients with a too short or too „mild“ therapy only with the isosonode silver amalgam in a serial pack beginning with potency D6, we measured a value improvement, which seems to be wrong, because when this patient again was tested with a D4 ampule we received a clear response to D4. Because of this possible irritation of the EAV - diagnostics we rarely used the isonosode silver amalgam or mercurius sol..

A check of this exact fine tuning with EAV and the curing success through DMPS tests was not yet possible in this pilot study.

Evaluation of 266 patients (examination and questionnaire):

å average age: 43.9 years

å standard deviation: 15.1

å 85 male, 181 female

å amalgam removal in 130 patients

å amalgam detoxification in 144 patients

å skin allergy test positive in 13.1 %

Therapy (sometimes two or more drugs are combinated)

å DMPS                                16.9 %

å zinc                                     58.4 %

å selenium                              57.7 %

å homeopathic drugs               47.6 %

å vitamines                             30.7 %

å other                                   11.5 %

å secondary diseases (intestinal dysbacteria, sinusitis); therapy in 78 patients

Improvement of the complaints in patients with amalgam removal and detoxification over 3-6 months: 80.4 %


improvement through removal of amalgam and detoxification    

80,4% (n=130)

å controls have shown that often 6 - 12 months of therapy are necessary


Improvement in single symptoms:  

number of patients (%)              improvement in %

mouth symptoms

gingiva bleeding                                                    39 (20.8 %)                                        79.5 %

grinding of teeth                                                    34 (13.1 %)                                        79.1 %

glossopyrosis                                                       18 (  9.7 %)                                        88.9 %

dry mouth                                                            28 (15.4 %)                                        92.8 %

metallic taste                                                        58 (24.6 %)                                        96.5 %




contact eczema                                                    26 (10.5 %)                                        61.5 %

food allergy                                                          32 (16.5 %)                                        62.5 %

hay fever                                                              34 (18.4 %)                                        50.0 %

eczema (neurodermatitis)                                      27 (13.5 %)                                        51.8 %

asthma/chronic bronchitis (n 45)                              9 (20.0 %)                                        55.5 %

itching/pruritus                                                         27 (19.5 %)                                        75.0 %

chronic/frequent infections or inflammatory irritations

nose                                                                     62 (32.0 %)                                        74.2 %

paranasal sinuses                                                  61 (29.6 %)                                        78.7 %

pharynx                                                                56 (27.8 %)                                        83.9 %

chronic headache/migraine                                    49 (19.5 %)                                        77.5 %

vertigo                                                                 48 (26.3 %)                                        75.0 %

low blood pressure                                               40 (21.8 %)                                        50.0 %

neurologic symptoms                                        

aboulia/fatigue                                                       89 (46.9 %)                                        69.7 %

lack of concentration                                            75 (41.3 %)                                        72.0 %

depressive mood                                                  76 (40.9 %)                                        80.3 %

extreme nervousness                                             55 (30.4 %)                                        83.6 %

insomnia                                                               52 (28.5 %)                                        76.9 %

tremor                                                                 34 (17.6 %)                                        70.6 %

dysopia                                                                41 (19.5 %)                                        53.6 %

tinnitus                                                                   31 (17.2 %)                                        48.4 %

arrhythmias                                                          29 (18.4 %)                                        62.1 %

increased sweating                                               42 (22.5 %)                                        61.9 %

aching back                                                          72 (39.4 %)                                        61.1 %

rheuma                                                                  19 (11.2 %)                                         73.7 %

acne (n = 70)                                                         8 (11.4 %)                                        50.0 %

alopecia/loss of hair                                              32 (19.5 %)                                        59.4 %

urgency                                                                39 (21.0 %)                                        61.5 %

constipation                                                          26 (15.7 %)                                        76.9 %

meteorism                                                            64 (31.5 %)                                        62.5 %

diarrhea                                                               39 (15.4 %)                                        69.2 %

inflammation of the eye                             33 (17.6 %)                                        63.3 %



Summarized we can say that in spite of the inclusion of the only moderate improvements, we have a distinct proof for the abilities of an orthomolecular and homeopathic therapy of the chronic mercury poisoning, even with a renunciation of DMPS in most of the cases.

We were especially surprised when we saw the successes in those patients with neurological symptoms.




improvement of depressive mood

80,3% (n=50)



å enormous improvements were achieved in patients with chronic infections

improvement  of sinusitis

80,4% (n=46)  

In patients with allergies the results were worse (e.g. hay fever 50% improvement).

In one group of patients with an additional and more intensified naturopathic treatment of the associated diseases this percentage increased up to 70%.

detected associated diseases

Mycosis and intestinal dysbiosis were found in more than 90% of those patients who were diagnosed with the comprehensive EAV test. By means of an intensified amalgam detoxification and microbiological therapy we treated these concomitant diseases most of the time successfully, even without antimycotics. Microbiological examinations of the faeces were only necessary in a few cases.

Toxins of the housing space and the accumulation of pollutants at the place of employment were traceable in about 20% as an additional stress factor and have been treated naturopathically (therapy with isonosodes, phyotherapeutical-homeopathical detoxification, vitamines, avoidance of exposition to these toxins).

In Patients with rheumatic diseases and cancer we often diagnosed a chronic infection of the teeth by EAV(most of the time without symptoms). For further treatment and control we sent those patients to a dentist.

Other concomitant diseases that were treated partly homeopathically are chronic infections of the pharynx and the paranasal sinuses.

The number of those patients who were treated with DMPS was too small and the duration of the therapy was too short to compare them with the others. Only very sick patients chose this treatment.



The Marburg amalgam detoxification study proves again the necessity of a prohibition of  amalgam fillings.

Numerous chronic diseases which are increasing threateningly and thus are responsible for the also increasing costs in our health system, are connected with the use of amalgam.


å The extreme augmentation in sugar consumption in the last 100 years from 10 to 100 g sugar per person and day (DGE - german society for nourishment) has led to an enormous increase of caries and has so allowed amalgam to be established as the „cheapest solution“ to this problem.


å A consistant and logical demand for the financiation of the removal of amalgam and the replacement of amalgam through gold alloys (without palladium) is the introduction of a sugar tax of 5 DM (Deutschmark) per KG.

Nearly 15 milliards DM would unburden our public health service and e.g. one bar of chocolate would only be 30 Pfennige more expensive.

The producers would so help to fight the concomitant diseases.



The publication of the detailed results will happen in a new edition of „Amalgam - und was dann?“ (sick through amalgam - what can I do ?) by our institute.



W.H.Koch und M.Weitz:Amalgam, Wissenschaft und Wirklichkeit.Ökoinstitut, Freiburg im Breisgau.

Drasch, Schupp, Riedel: Einfluß von Amalgamfüllungen auf die Quecksilber-konzentration in menschlichen Organen.Dt.Zahnärztl.Z. 47 (1992) 490 - 496.

F.Perger: Amalgamtherapie, in Kompendium der Regulationspathologie und -therapie. Sonntag-Verlag 1990.

K.H.Friese: Amalgamtherapie für Ärzte und Zahnärzte. Panta 3 (1992 ) Haug-Verlag.

P.Smrz: Amalgam, die verharmloste Zeitbombe. Hipokrates Akademie-Verlag, Ulm.

M.Daunderer: Handbuch der Amalgamvergiftung, Diagnostik, Therapie, Recht. 1992/ 1995. Ecomed-Verlag

R.L.Silberud: Die Beziehung zwischen Quecksilber aus Zahnamalgam und psychischer Gesundheit. Dt. Übersetzung in:

U.Hofmann: Krank durch Amalgam - und was dann ? 1995. GeMUT-Verlag, Marburg

Danz, Leber, Schneider, Weber: Homöopathischer Diagnostikvergleich mit EAV in Blindstudie.Ärztezeit.f.Naturheilverfahren 9 ( 1993 )

H.Rossmann: Kompendium der Elektroakupunktur nach Voll. 1995. Haug-Verlag.


Anschrift : Amalgamberatung Institut für Naturheilverfahren

Uferstr. 1  D35037 Marburg o6421 68430 /684320 Weber


amalgam counsel - Institute for Naturopathic Medicine - Uferstr.4 - D35037 Marburg - Tel.: 06421/684320, 61140 - Fax 06421/684350

A 16     Tsuei, J.J., C. Chun and C.Y. Lu. »Study of Pesticide Residues in the    bodies of Workers at a Chemical Factory by Bioenergetic Measurements«.   R.O.C. National Science Council Reports,  Apr. 1988 - Mar. 1989

                        - Comparative-descriptive study, N=162

                        - Only available in Chinese (Übersetzung geplant, Institut f.N.Marburg)

A 17     Chang, Y. and J.J. Tsuei. »Correlation Study between Acupuncture Points,        Meridians and Internal Organs of Rats by Bioenergetic Measurements«.          R.O.C. National Science Council Reports, Aug. 1988 - July 1989

                        - Descreptive study

                        - Abstract currently available in English

A 18     Lui, W.C. and J.J. Tsuei. »Bioenergetic Measurements of Patients with             Chronic Fatigue Syndrome«. Scientific Reports of the Foundation for East-   West Medicine, 1990.             - Comparative-descriptive study, N=10

                        - Abstract currently available in English

A19      Tsuei, J.J. and P- Chang. »A Comparative Study of Herbal to Allopathic            Treatments for Allergic Rhinitis«. Paper presented to the Association of    Allergy and Asthma of the Republic of China, No. 1991

                        - Descreptive study, N=60        - Abstract currently available in English

A 20     Tsuei, J.J. and F.M.K. Lam Jr. »Observation in the Clinical Application of         Electroacupuncture According to Voll«. The third joint conference of the          World Congress of Clinical Medicine and Pharmacy and the International             Symposium on Acupuncture and Moxibustion R.O.C., Program and             Abstract of Papers, Nov.25-27, 1990, pages 127-128

                        - Presentation   - Abstract currently available in English

A 21     Chen, K.C., et al. »Transient Responses of an Human Body to a Small DC        Voltage and Electrical Properties of Meridians«. Paper presented to the       WHO International Congress on Traditional Medicine (Beijing) Oct.21, 1991.

                        - Descriptive study        - Synopsis currently available in English**

A 22     Tsuei, J.J. »The Clinical Value of Electrodermal Screening Test«. Paper            presented to the WHO International Congress on Traditional Medicine          (Beijing) Oct. 21, 1991.

                        - Presentation               - Synopsis currently available in English**

A 23     Tsuei, J.J., W. K. Wang and P.T. Yang. »The Study of Bioenergetic     Screening Model for Hypertension.“ R.O.C. National Science Council       Reports, June 1991 - Nov. 1992         - Case control study, N=405 - Synopsis currently available in English

A 24     Tsuei, J.J. W.K. Wang, K.G. Chen. »Comparative Study of 400 Subjects           Electro-dermal Screening Test with Contemporary Routine Physical            Examination, Including: Urine, Stool, Biochemistry, X-ray, EKG, and      Dental Evaluation, and Traditional clinical Diagnosis«. R.O.C. National            Science Council Reports, Aug. 1992-July 1993.            - Comparative-descriptive study, N=139

                        - Abstract currently available in English

A 25     Chen, S.Y., C.T. Liu. »Study of Galvanic Dental Voltages; The             Relationship of Buccal Currents and Voltages in the Mouth and the     Meridian System of the Body«. R.O.C. National Science Council Reports,      Aug. 1992 - July 1993.

                        - Comparative-descriptive, N=160 - Abstract currently available in English

A 26     Tsuei, J.J. »The Past, Present and Future of the Electrocermal Screening           System (EDSS)«. Journal of Advancement in Medicine, Winter 1995.

                        - Review article, 53 references             - In English

** Available in : Tsuei , Julia J., editor. International Congress on Traditional Medicine (Beiijing) ‘91), Symposium & Workshop on October 21, 1991, Modern Interpretation of »Qi« and »Blood« -- Bioenergetic Medicine, Taipei: Foundation For East-West Medicine, 1991

A 21 : J.J.Tsuei, National Yangming Universität in Taipei in Taiwan gibt 1995 mit „The Past, Present and Future of the Electrodermal Screening System ( EDSS ) eine Zusammenfassung der obengenannten Studien und beschreibt die positiven  Möglichkeiten der EAV.(  Journal of Advancement in Medicine, Vol.8.Nr.4, 1995, S.217-232, Human Sciencess Press, Inc. )

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